當前位置: 華文星空 > 寵物

我家的貓得了冠狀病毒怎麽辦?

2021-09-23寵物
「感染冠狀病毒(FCoV)」,是 腸炎 還是 傳腹 呢?

這可以是 貓腸道冠狀病毒(FCoV) 可以是 貓傳染性腹膜炎病毒(FIPV)

前者 廣泛存在 於貓的腸道中且有 強傳染性 ,後者具有 極強的致死性 [1]

傳染性有多強呢,如果一群貓中有 一只為陽性 ,那麽這群貓中的 9成已經被感染了

病毒性腸炎與傳染性腹膜炎呈現高度關聯性 ... [2] [3]

遺憾的是, FCoV與FIPV之間沒有明顯的界限。

2012年,貓傳腹研究泰鬥Neils C Pedersen教授研究發現 FIPV其實是FCoV的變種 [4]

就是這位老爺子研究了50年FIP,提出了376和441兩種知名治療方案

變異之前, FCoV 只能引起一些 胃腸炎癥 ,是一種 「自限性疾病(Self-limited Disease)」 ,病程可以自行停止,腸道上的損傷也能自愈

但一旦貓咪抵抗力降低,FCoV就會大量復制,像新冠病毒一樣,復制多了,難免出現變異——於是就有了FIPV [5] [6] [7] [8]

FIPV 引發的疾病,就是令諸多獸醫頭禿、鏟屎官聞風喪膽的 傳染性腹膜炎(FIP)

也正因此, FIP多發於抵抗力低的幼貓(<1歲)和老貓(>11

參考

  1. ^ Kipar A , Baptiste K , Barth A , et al. Natural FCoV infection: cats with FIP exhibit significantly higher viral loads than healthy infected cats[J]. Journal of Feline Medicine & Surgery, 2006, 8(1):69-72.
  2. ^ Pedersen N C , Boyle J F , Floyd K , et al. An enteric coronavirus infection of cats and its relationship to feline infectious peritonitis.[J]. American Journal of Veterinary Research, 1981, 42(3):368-377.
  3. ^ Tekelioglu B K , Berriatua E , Turan N , et al. A retrospective clinical and epidemiological study on feline coronavirus (FCoV) in cats in Istanbul, Turkey[J]. Preventive Veterinary Medicine, 2015, 119(1-2):41-47.
  4. ^ Pedersen N C , Liu H , Scarlett J , et al. Feline infectious peritonitis: role of the feline coronavirus 3c gene in intestinal tropism and pathogenicity based upon isolates from resident and adopted shelter cats.[J]. Virus Research, 2012, 165(1):17-28.
  5. ^ Scherk M A . DISEASE INFORMATION FACT SHEET.
  6. ^ Paltrinieri S , Metzger C , Battilani M , et al. Serum α1-acid glycoprotein (AGP) concentration in non-symptomatic cats with feline coronavirus (FCoV) infection[J]. Journal of Feline Medicine & Surgery, 2007, 9(4):271-277.
  7. ^ Tekelioglu B K . Seroepidemiological and Clinicopathological Study of Feline Coronavirus (FCoV) and Feline Infectious Peritonitis (FIP), Could Guide to SARS-CoV-2 (COVID-19) in 'One Health' Approach. 2020.
  8. ^ Vennema H , Poland A , Foley J , et al. Feline Infectious Peritonitis Viruses Arise by Mutation from Endemic Feline Enteric Coronaviruses[J]. Virology, 1998, 243(1):150-157.