对特发性少弱畸精症患者，每天补充辅酶Q10，为期3个月后，能显著改善小蝌蚪形态，持续12个月，能提高浓度和活性，总体妊娠率也有所提高，参考用量为：200-600mg/天（1-3）。
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- Nadjarzadeh, A.; Sadeghi, M.R.; Amirjannati, N.; Vafa, M.R.; Motevalian, S.A.; Gohari, M.R.; Akhondi, M.A.; Yavari, P.; Shidfar, F. Coenzyme Q10 improves seminal oxidative defense but does not affect on semen parameters in idiopathic oligoasthenoteratozoospermia: A randomized double-blind, placebo controlled trial. J. Endocrinol. Investig. 2011, 34, e224–e228.111.
- Safarinejad MR. The effect of coenzyme Q10 supplementation on partner pregnancy rate in infertile men with idiopathic oligoasthenoteratozoospermia: an open label prospective study. Int Urol Nephrol 2012,,44(3), 689-700 (2012)
